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Title: Biomaterials and mesenchymal stem cells for Biomaterials and mesenchymal stem cells for regenerative medicine

Author: Zippel N, Schulze M, Tobiasch E.

Journal or Ebook Name: Recent Pat Biotechnol.

Volume, Issue, Year and Pages : 2010 Jan;4(1):1-22.

Link: http://www.ncbi.nlm.nih.gov/pubmed/20201799

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Recent Patents on Biotechnology

 

 

2010, 4, 1-22 1

1872-2083/10 $100.00+.00 © 2010 Bentham Science Publishers Ltd.

Biomaterials and Mesenchymal Stem Cells for Regenerative Medicine

Nina Zippel, Margit Schulze and Edda Tobiasch*

Department of Natural Sciences, University of Applied Sciences Bonn-Rhein-Sieg, von-Liebig-Straße 20, D-53359

Rheinbach, Germany

Received: September 2, 2009; Accepted: October 26, 2009; Revised: November 7, 2009

Abstract:

 

 

The reconstruction of hard and soft tissues is a major challenge in regenerative medicine, since diseases or

traumas are causing increasing numbers of tissue defects due to the aging of the population. Modern tissue engineering is

increasingly using three-dimensional structured biomaterials in combination with stem cells as cell source, since mature

cells are often not available in sufficient amounts or quality. Biomaterial scaffolds are developed that not only serve as

cell carriers providing mechanical support, but actively influence cellular responses including cell attachment and

proliferation. Chemical modifications such as the incorporation of chemotactic factors or cell adhesion molecules are

examined for their ability to enhance tissue development successfully. E.g. growth factors have been investigated

extensively as substances able to support cell growth, differentiation and angiogenesis.

Thus, continuously new patents and studies are published, which are investigating the advantages and disadvantages of

different biomaterials or cell types for the regeneration of specific tissues. This review focuses on biomaterials, including

natural and synthetic polymers, ceramics and corresponding composites used as scaffold materials to support cell

proliferation and differentiation for hard and soft tissues regeneration. In addition, the local delivery of drugs by scaffold

biomaterials is discussed.

Keywords

 

 

: Angiogenesis, bioactive factors, biomaterials, bone, cartilage, ceramics, differentiation, hard and soft tissue,

mesenchymal stem cells, polymers, proliferation, regenerative medicine, scaffolds, tissue engineering.

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Journal of Power Sources 167 (2007) 482–485

Short communication

Hydrolytic cleavage of ammonia-borane complex for hydrogen production

Nahid Mohajeri , Ali T-Raissi, Olawale Adebiyi

Hydrogen R&D Division, Florida Solar Energy Center, University of Central Florida 1679 Clearlake Rd., Cocoa, FL 32955, USA

Received 3 October 2006; received in revised form 15 February 2007; accepted 19 February 2007

Available online 1 March 2007

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Title: Biomaterials and mesenchymal stem cells for Biomaterials and mesenchymal stem cells for regenerative medicine Author: Zippel N, Schulze M, Tobiasch E. Journal or Ebook Name: Recent Pat Biotechnol. Volume, Issue, Year and Pages : 2010 Jan;4(1):1-22. Link: http://www.ncbi.nlm.nih.gov/pubmed/20201799 @};-
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